Posted 19 января 2021,, 06:11

Published 19 января 2021,, 06:11

Modified 24 декабря 2022,, 22:37

Updated 24 декабря 2022,, 22:37

Scientists told how to determine the risk of death from covid

Scientists told how to determine the risk of death from covid

19 января 2021, 06:11
An early indicator for determining severe consequences and death from coronavirus infection can be the measurement of the level of mitochondrial DNA in the blood of patients infected with covid.

This was stated by researchers from the University of Washington School of Medicine in St. Louis, whose research is described on the website of the educational institution, and the results of the work are published on the bioRxiv preprint portal.

Experts took samples of acellular plasma from 97 patients diagnosed with COVID-19 pain. They also measured the level of circulating mitochondrial DNA in these samples. The biomaterial was obtained immediately after the patients sought medical help.

It turned out that circulating mitochondrial DNA was dramatically increased in those for whom the disease became fatal, and in those who required hospitalization in an intensive care unit or connection to a ventilator system.

The scientists explained that elevated levels of mitochondrial DNA are a risk factor regardless of age, gender, or underlying medical conditions.

According to the study authors, the relationship between the appearance of mitochondrial DNA released from cells and blood flow and the risk of complications and death from coronavirus remains uncertain. But it is known that this is a sign of a certain type of cell death in the body.

On average, the level of mitochondrial DNA was about ten times higher in patients who developed lung dysfunction and who later died. The risk of the need for a ventilator increases sixfold when the level of mitochondrial DNA rises, treatment in intensive care - threefold, and the risk of death - twofold.

Meanwhile, the number of victims of coronavirus infection in the world has exceeded two million. At the same time, China was warned that this is only a small part of the deaths, compared to what the planet can expect in the coming months - by March 2021, the number of victims of coronavirus infection may exceed five million. Countries with more than five million coronavirus infections include the United States, India and Brazil.