Immortality is canceled: biophysicists believe that humans will not be able to live longer than 150 years

This forecast was given by experts in the field of biology and biophysics from the Singapore-based biotech company Gero and the Roswell Park Cancer Center in Buffalo, New York, according to the Daily Mail.

In their work, the scientists relied on medical data from hundreds of thousands of volunteers from the UK and the United States, as well as the results of two longitudinal DNA studies. The scientists passed all the information through the artificial intelligence system they created - DOSI ("Dynamic indicator of the state of the organism"). It turned out that at the age of 120 to 150 years, the human body finally loses its ability to recover.

Throughout most of the history of mankind, information about which is available to us, the average life expectancy was from 20 to 40 years. Today, in developed countries, it exceeds 80 years - thanks to improved nutrition, clean water, compliance with sanitary and hygienic standards and a high level of medicine. In the future, people will be able to live even longer - through genetic manipulation, calorie restriction, and the invention of new drugs. However, human life will have a limit anyway.

Researchers have found two key parameters responsible for lifespan: lifestyle factors and how the body responds to them. The first is our biological age: it is determined by stress, lifestyle and disease. The second is the stability of the organism, that is, how quickly it is able to return to normal after shocks.

Aging is associated with the appearance of the so-called zombie cells in the body, which are alive but are no longer able to function properly. These cells are associated with a wide variety of age-related conditions, from arthritis to Alzheimer's disease. Even in those who do not suffer from serious chronic diseases, the number of zombie cells increases with age, and the body's resistance decreases. An aging person needs more and more time to recover from shocks, and shorter and shorter periods spent in a physiological state close to optimal. Therefore, even the most effective prevention and treatment of age-related diseases can increase the average life expectancy, but cannot affect the maximum one. Unless, of course, innovative anti-aging treatments emerge.

The researchers also developed an iPhone app called GeroSense that calculates the rate of biological aging and the maximum lifespan of a user based on their physical activity.

The research results are published in the journal Nature Communications.