Posted 12 июля 2021,, 12:20

Published 12 июля 2021,, 12:20

Modified 24 декабря 2022,, 22:37

Updated 24 декабря 2022,, 22:37

Geneticists have found a way to lengthen the life of males: this is castration

Geneticists have found a way to lengthen the life of males: this is castration

12 июля 2021, 12:20
Scientists conducted an experiment with rams and found that after removing the testes in animals, DNA aging is delayed, due to which castrates live 60% longer. Probably, this pattern extends to humans, the authors of the study suggest.

It is known that the majority of women are worried about partners. This applies to humans, sheep, and other mammals. Epigeneticists from the University of Otago, New Zealand, conducted an experiment that shed light on the effects of male hormones on aging and longevity, according to the Daily Mail.

Scientists have compared how DNA ages in sheep. To do this, they created a so-called epigenetic clock for animals, which measures biological aging based on data from chemical tags known as methyl groups. Having studied a large number of animals, geneticists have found that the epigenetic hours of groomed rams, or rolls, run slower than that of their full-fledged counterparts. After castration, the characteristics of some sections of DNA in rams became feminine - even though formally they remained males.

Scientists have developed a way to measure biological age in more than 200 species of different mammals and found that the general laws of aging apply to all. So, it is likely that DNA changes associated with the influence of male hormones are characteristic not only for sheep, but also for other species.

The study authors also studied the effects of male hormones on tissues using mice and found large differences between DNA samples from males and females in tissues where male hormone receptors are present, such as in the skin, brain and kidneys. But tissues without expression of male hormone receptors, as a rule, were the same regardless of gender.